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Biopharm

Biomarker for Prediction of Early Pregnancy Loss

Biomarker for Prediction of Early Pregnancy LossAvailable for: Co-development and/or licensingSummaryUCL researchers have identified two bio-markers that differentiate women who miscarry during pregnancy from those who do not miscarry among a group of high-risk patients.The Technology and its AdvantagesCurrently there are no validated biochemical tests to predict a subsequent miscarriage in early pregnancy. Many pregnant

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Physical Sciences

Passive Wireless Detection System

Available for: Licensing and Joint DevelopmentSummaryA team of researchers at UCL’s Department of Electronic and Electrical Engineering, have developed a method for detection and tracking using existing wireless signals (WiFi) present in the everyday environment.The Technology and its advantagesThe Passive Wireless Detection System uses software defined radio architecture, which includes proprietary signal processing and a

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Biopharm

Basit:Microparticles for oral drug delivery

Available for: Exclusive drug-specific licenceSummaryAccurateand rapid releaseof drugsin specific regions of the GI tract following transit through the stomach is an advantage for several reasons, such as local therapy, improved uptake through concentration effect and rapid systemic delivery. We have developed a drug form which allows delayed release and is administered in a liquid suspension.The

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Physical Sciences

X-Ray Phase Contrast Imaging for Enhanced Threat Detection and Composite Material Analysis

X-Ray Phase Contrast Imaging for Enhanced Threat Detection and Composite Material AnalysisAvailable for: Licensing and co-developmentSummaryProfessor Robert Speller and his team at University College London have developed a novel phase contrast x-ray technology with potential for improved image quality and enhanced diagnostic potential when applied to non-destructive testing, homeland security and material science applications. This

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Biopharm

Silica Wool

Porous superhydrophobic/ superoleophillic material for oil-water separation and remediationAvailable for: Exclusive and Non-Exclusive LicensingSummaryThe technology comprises a porous material having both superhydrophobic and superoleophillic properties and is suitable for water-oil separation /filtration and remediation. Laboratory results achieved to date have used functionalised silica wool and have demonstrated high oil-water separation efficacy. The best performing solvent

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Biopharm

Preventing amyloid fibril formation. The recently identified pathogenic D76N ß2 microglobulin variant which readily forms amyloid fibrils under physiological conditions in vitro is a crucial new tool for mechanistic studies and screening studies

We have characterized the first naturally occurring structural variant of human beta-2M, D76N, as the amyloid fibril protein in a family with a new phenotype of late onset, fatal, hereditary systemic amyloidosis (Valleix et al N Engl J Med). We have discovered a method suitable for the fibrillogenesis of this protein that is consistent with

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Biopharm

Modulation of hedgehog signalling for treatment of cancers and inflammatory disease

Modulation of hedgehog signalling for treatment of cancers and inflammatory diseaseAvailable for: License or CollaborationSummaryResearchers at the UCL Institute of Child Health have discovered that modulating the hedgehog signalling family proteins has implications for treating certain cancers and inflammatory diseases. Market OpportunityDesert Hedgehog (Dhh) negatively regulates both normal and stress (anaemia)-induced erythropoiesis in the bone

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Biopharm

Formulations for the Prevention of Neural Tube Defects

Formulations for the Prevention of Neural Tube DefectsAvailable for: LicenseSummaryExploring ways to prevent birth defects,researchers at the UCL Institute of Child Health have discovered novel supplements that if taken in pregnancy can reduce the chance of the baby having neural tube defects such as spina bifida or anencephaly. These are important in pregnancies where folic

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Biopharm

Superior X-Ray Imaging for Early Detection of Breast Cancer

Superior X-Ray Imaging for Early Detection of Breast CancerAvailable For: Licensing and co-developmentSummaryProfessor Robert Speller and his team at University College London have developed a novel phase contrast x-ray technology with the potential for improved image quality and enhanced diagnostic potential when applied to mammography. This technology will provide earlier more accurate detection of breast

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Physical Sciences

Non-Volatile Memory - Resistive Random Access Memory RRAM

Available for: Licensing and Joint DevelopmentSummaryResearch within the Department of Electronic and Electrical Engineering (E&EE) at UCL has led to the realisation of a new memory device, based on resistive switching which has the potential to be integrated directly onto silicon. The memory device exhibits very fast switching with high resistance contrast, requiring low switching

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