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External Projects

OpSAFE

Available For: Exclusive or Non-Exclusive licenseSummaryOpSAFE is a medical device that enables touch free use of OsiriX MD image viewer for medical images.The Technology and its AdvantagesFully CE marked, the OpSAFE device comprises plug in software, foot pedal and LEAP motion controller. Staff can remain scrubbed in and there is no need for an additional

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Biopharm

Drusen Diagnostic

Drusen Diagnostic Available for: Exclusive/Non-exclusive licensing Summary AMD is the most common cause of irreversible vision impairment in the Western world. There is currently no cure for AMD and all the efforts concentrate on managing symptoms and early detection and treatment of AMD significantly reduces vision impairment. Most patients are diagnosed at advanced stages of

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Biopharm

Leukocyte labelling for detecting inflammation

Available for: Exclusive/Non-Exclusive licensing Summary Inflammation plays a role in many diseases including sight-threatening diseases of the eye such as uveitis. Recently, inflammation has also been shown to drive the processes of pathological angiogenesis in Age-related Macular Degeneration (AMD) and Diabetic Retinopathy (DR). Current methods for monitoring inflammation have limits and include direct visualisation by

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Biopharm

Lrg-1 antagonists: Direct effect upon cancer cells

LRG1 antagonists for neovascularisation, cancer and aberrant scaring Available for: Exclusive/Non-exclusive licensing Summary The formation of new blood vessels by angiogenesis is a key feature of number of diseases including Age-related Macular Degeneration (AMD), Proliferative Diabetic Retinopathy (PDR), atherosclerosis, rheumatoid arthritis and cancer. Vascular Endothelial Growth Factors (VEGFs) and their receptors have been previously identified

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Biopharm

Treatment of fibrosis with ALDH inhibitors

Treatment of fibrosis with ALDH inhibitors Available for: Exclusive Licensing Summary Fibrosis is the formation of excess fibrous connective tissue in response to injury and inflammation. If it happens in response to injury it is also referred to as scarring. Fibrosis is associated with conditions such as cystic fibrosis, cirrhosis, mucous membrane pemphigoid (MMP), pulmonary

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Biopharm

H4R antagonists for uveitis and other inflammatory diseases

Available For: Exclusive Licensing Summary Histamine is a pleiotropic mediator involved in a variety of physiological processes including neurotransmission, endocrine and vascular processes. It also plays a key role in inflammation and binding to one of its four receptors (H1R-H4R). Researchers at UCL Institute of Ophthalmology have shown that targeting H4R receptor in the central

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Biopharm

New genetic marker for Age-related Macular Degeneration (AMD)

Available for: Exclusive/Non-exclusive licensing Summary AMD is the most common cause of irreversible vision impairment in the Western world and susceptibility to it is influenced by age, environmental and genetic factors. There is currently no cure for AMD and all the efforts concentrate on managing symptoms and early detection and treatment of AMD significantly reduces

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Biopharm

Early Diagnosis of Alzheimer's Disease

Early Diagnosis of Alzheimer’s Disease Available for: Exclusive Licensing/Non-exclusive Licensing Summary Alzheimer Disease (AD) is the most common neurodegenerative disorder affecting half of all the people above 80 years of age. The available diagnostic methods are expensive and are not available to all patients. An easily detectable biomarker that could be used for diagnosis and

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Engineering

Superior X-Ray Imaging for Early Detection of Breast Cancer

Superior X-Ray Imaging for Early Detection of Breast CancerAvailable For: Licensing and co-developmentSummaryProfessor Robert Speller and his team at University College London have developed a novel phase contrast x-ray technology with the potential for improved image quality and enhanced diagnostic potential when applied to mammography. This technology will provide earlier more accurate detection of breast

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Physical Sciences

Non-Volatile Memory - Resistive Random Access Memory RRAM

Available for: Licensing and Joint DevelopmentSummaryResearch within the Department of Electronic and Electrical Engineering (E&EE) at UCL has led to the realisation of a new memory device, based on resistive switching which has the potential to be integrated directly onto silicon. The memory device exhibits very fast switching with high resistance contrast, requiring low switching

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