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Biopharm

Imatinib and other ABL inhibitors to treat ocular neovascularisation

p { margin-top: 0px;margin-bottom: 12px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Available for: Exclusive LicensingSummaryRetinal and choroidal diseases are the most common cause of vision loss in the

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Biopharm

New lentiviral platform eliminating packaging sequences from the transcribed DNA region

p { margin-top: 0px;margin-bottom: 12px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Available for: Exclusive/Non-exclusive LicensingSummaryAll lentiviral vectors described to date contain packaging sequences necessary for the viral RNA

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Biopharm

Treatment of fibrosis with ALDH inhibitors

p { margin-top: 0px;margin-bottom: 0px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Treatment of fibrosis with ALDH inhibitorsAvailable for: Exclusive LicensingSummaryFibrosis is the formation of excess fibrous connective tissue

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Biopharm

Novel Therapy for Polycystic Kidney Disease (PKD)

p { margin-top: 0px;margin-bottom: 12px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Available for: Exclusive/Non-Exclusive LicensingSummaryPolycystic kidney disease is the most common inherited cause of kidney failure, affecting 1

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Biopharm

Silica Wool

Porous superhydrophobic/ superoleophillic material for oil-water separation and remediationAvailable for: Exclusive and Non-Exclusive LicensingSummaryThe technology comprises a porous material having both superhydrophobic and superoleophillic properties and is suitable for water-oil separation /filtration and remediation. Laboratory results achieved to date have used functionalised silica wool and have demonstrated high oil-water separation efficacy. The best performing solvent

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Biopharm

Preventing amyloid fibril formation. The recently identified pathogenic D76N ß2 microglobulin variant which readily forms amyloid fibrils under physiological conditions in vitro is a crucial new tool for mechanistic studies and screening studies

We have characterized the first naturally occurring structural variant of human beta-2M, D76N, as the amyloid fibril protein in a family with a new phenotype of late onset, fatal, hereditary systemic amyloidosis (Valleix et al N Engl J Med). We have discovered a method suitable for the fibrillogenesis of this protein that is consistent with

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Biopharm

H4R antagonists for uveitis and other inflammatory diseases

p { margin-top: 0px;margin-bottom: 12px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Available For: Exclusive LicensingSummaryHistamine is a pleiotropic mediator involved in a variety of physiological processes including neurotransmission,

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Biopharm

Modulating Sonic Hedgehog signalling for treatment of Autoimmune Disease and Inflammation

p { margin-top: 0px;margin-bottom: 12px;line-height: 1.15; } body { font-family: ‘Verdana';font-style: Normal;font-weight: normal;font-size: 16px; } .Normal { telerik-style-type: paragraph;telerik-style-name: Normal;border-collapse: collapse; } .TableNormal { telerik-style-type: table;telerik-style-name: TableNormal;border-collapse: collapse; } .Hyperlink { telerik-style-type: character;telerik-style-name: Hyperlink;color: #0000FF;text-decoration: underline;border-collapse: collapse; } Available for: Exclusive/Non-exclusive licensingSummaryChronic inflammation plays role in diseases such as asthma, atopic skin conditions and cancer.

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Biopharm

Modulation of hedgehog signalling for treatment of cancers and inflammatory disease

Modulation of hedgehog signalling for treatment of cancers and inflammatory diseaseAvailable for: License or CollaborationSummaryResearchers at the UCL Institute of Child Health have discovered that modulating the hedgehog signalling family proteins has implications for treating certain cancers and inflammatory diseases. Market OpportunityDesert Hedgehog (Dhh) negatively regulates both normal and stress (anaemia)-induced erythropoiesis in the bone

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Biopharm

Formulations for the Prevention of Neural Tube Defects

Formulations for the Prevention of Neural Tube DefectsAvailable for: LicenseSummaryExploring ways to prevent birth defects,researchers at the UCL Institute of Child Health have discovered novel supplements that if taken in pregnancy can reduce the chance of the baby having neural tube defects such as spina bifida or anencephaly. These are important in pregnancies where folic

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