Spinout News

UCLB spin-out Spirogen sold to AstraZeneca for $200 million

21 October 2013


Spirogen, a biotechnology company spun-out of UCL by UCL Business in 2001, has been sold to AstraZeneca.

The company – which develops novel therapeutics to target cancers – was sold to AstraZeneca’s MedImmune unit for an initial $200 million, with a payment of a further $200 million should Spirogen meet development targets. The funds will be used to bolster the company’s oncology pipeline.

In particular, Spirogen focuses on antibody-drug conjugate technology; technology which has the potential to directly target cancer tumours while leaving healthy cells intact.

The cutting-edge technologies developed by Spirogen and ADC Therapeutics complement MedImmune’s innovative antibody engineering capabilities, enabling us to accelerate antibody-drug conjugates into the clinic,” said MedImmune Executive Vice President Bahija Jallal.

Spirogen CEO Dr Chris Martin said: “This deal reflects the very significant progress made by our scientists, most notably over the last two years, as we have applied our warhead and linker technologies to the development of highly potent and specific ADCs.

“We believe that PBD-armed antibody-drug conjugates will emerge as a critical component in the next generation of cancer biologics with the potential to make a difference for oncologists and their patients. We look forward to combining our world class capabilities in this area with MedImmune’s ability to develop this exciting class of oncology drugs.

About UCLB
UCLB is a leading technology transfer company that supports and commercialises research and innovations arising from UCL, one of the UK’s top research-led universities.

UCLB has a successful track record and a strong reputation for identifying and protecting promising new technologies and innovations from UCL academics. It invests directly in development projects to maximise the potential of the research and manages the commercialisation process of technologies from the laboratory to market.

UCLB supports UCL’s Grand Challenges of increasing UCL’s positive impact on and contribution to Global Health, Sustainable Cities, Intercultural Interaction and Human Wellbeing.

For further information, please visit: www.uclb.com