Available technologies

SoftSCREEN – A Shape-shifting Capsule Robot for GI Endoscopy

Soft Shape-shifting Capsule Robot for Endoscopy based on Eversion Navigation (SoftSCREEN). A novel design for a capsule robotic system that propels itself through the gastrointestinal (GI) tract by means of a series of continuously everting elastic tracks (i.e. the tracks go from the inside of the capsule to the outside in a continuous manner) distributed all around its body.
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Neidle_Quadruplex-binding compounds – A novel anticancer strategy

We have a first-in-class optimized small-molecule drug candidate ready for IND enabling studies with superior efficacy and activity against pancreatic cancer compared to existing agents, together with a distinct mechanism of action.
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Pneumatically Attachable Flexible (PAF) Rails for Laparoscopic Surgery

A novel multi-purpose surgical technology for intra-operative organ imaging and safe organ manipulation.
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Drug Delivery System for Crossing the Blood Brain or Blood Retinal Barrier (UDDS)

The blood retinal barrier (BRB), and the blood brain barrier (BBB), represent a significant impediment to drug delivery to the eye and the brain, respectively. This lack of drug penetration has resulted in diseases, such as Age-related Macular Degeneration (AMD), Alzheimer's Disease and Stroke being extremely difficult to address.

Although therapies to eye disease such as AMD already exist, they are delivered by intraocular injections with high risk of side effects related to the administration, the most significant being retinal detachment. The current challenge is to develop drug-delivery systems that ensure transitions across these barriers in a safe and effective manner.
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OpSAFE

OpSAFE is a medical device that enables touch free use of OsiriX MD image viewer for medical images.
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Magnetic Microbubbles

Magnetic microbubbles can be injected into the blood stream and may be directed to a specific body location by the application of an external magnetic field. They enhance ultrasound images, and can be used to deliver, and promote uptake of, cargo molecules such as drugs, antibodies or DNA. They thus have many potential applications in clinical settings, as well as in both basic and medical research.
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Early Diagnosis of Alzheimer’s Disease

Alzheimer Disease (AD) is the most common neurodegenerative disorder affecting half of all the people above 80 years of age. The available diagnostic methods are expensive and are not available to all patients. An easily detectable biomarker that could be used for diagnosis and monitoring of AD is needed. Researchers at UCL Institute of Ophthalmology demonstrated that measuring drusen deposits in the periphery of the eye can be used as diagnostic method for AD.
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Self-Disinfecting Computer Keyboard

Ambient lighting conditions activate a proprietary keyboard surface resulting in disinfection. These keyboards can be used in healthcare facilities to help prevent the spread of healthcare acquired infections (HCAIs).
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Formulations for the Prevention of Neural Tube Defects

Exploring ways to prevent birth defects, researchers at the UCL Institute of Child Health have discovered novel supplements that if taken in pregnancy can reduce the chance of the baby having neural tube defects such as spina bifida or anencephaly. These are important in pregnancies where folic acid and other supplements are not as effective. A new patent has been filed we are supporting work to validate and test combinations in animal models.
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Smart Target Image-Guided Diagnosis and Treatment of Localised Prostate Cancer

SmartTarget is a technology developed in UCL's Centre for Medical Image Computing (CMIC) that enables image-directed tumour targeting during minimally invasive biopsy and therapy procedures for prostate cancer patients.
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