Available technologies

Ultra-Fast Fluidic Analysis

A research group at UCL have developed a new microfluidic-based method which can be used in combination with either chemical or optical heating-based denaturation to measure protein stability curves and calculate affinity constants from nanolitre sample volumes.

Measurement times are significantly reduced from standard methods and envisaged applications range from high-throughput drug discovery to healthcare diagnostics and pathogen detection.
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New Micro-Cantilever Configuration

A team at London Centre for Nanotechnology are developing a device that is already being used to detect the presence viruses, bacteria and proteins from a single sample. It is based on a cantilever sensing method and is configured to give binding energy information as well as a quantative assay. The new system has already displaced use of the commercially available system in the Lab as the virologists find the new configuration much easier to use. The project is currently supported by the EPSRC for research on HIV management.
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Formulations for the Prevention of Neural Tube Defects

Exploring ways to prevent birth defects, researchers at the UCL Institute of Child Health have discovered novel supplements that if taken in pregnancy can reduce the chance of the baby having neural tube defects such as spina bifida or anencephaly. These are important in pregnancies where folic acid and other supplements are not as effective. A new patent has been filed we are supporting work to validate and test combinations in animal models.
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Collagen for tendon repair

Collagen is the most widely distributed class of proteins in the human body and the use of collagen-based biomaterials in the field of tissue engineering is extensive. However collagen hydrogels typically have low mechanical strength, and accordingly may not be suitable for use in tendon and other tissue repair grafts without further processing. Whilst there are methods available to increase the strength of collagen, they are not suitable for fabrication of certain tissues as the shape of tissue needs to be “crafted” which leads to structural weakness, layer separation and heterogeneous cell distribution.
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New lentiviral platform eliminating packaging sequences from the transcribed DNA region

All lentiviral vectors described to date contain packaging sequences necessary for the viral RNA genome to be assembled into viral particles. These sequences are unnecessarily reverse transcribed into DNA and permanently integrate into target cells. The researchers at UCL Institute of Child Health have developed a lentiviral platform which does not reverse transcribe the packaging sequences into the target cells.
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III-V laser diodes on germanium substrates

The Photonics Research Group at UCL have recently developed and demonstrated a monolithically integrated III-V compound semiconductor photonic structure on a Silicon substrate. The monolithic III-V on Silicon device opens up new possibilities for integrated system-on-a-chip designs with high bandwidth and high data transfer rates.
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SnakeGrid Transformer for CAD

Based on research at UCL Civil, Environmental and Geomatic Engineering Department, SnakeGrid® Transformer is a plug-in software module for the Bentley MicroStation CAD package and allows the conversion of Bentley MicroStation design files "on the fly" between different SnakeGrids®, London Survey Grid, British National Grid settings and local grids such as the Reading Grid.
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Novel Percutaneous Heart Valve

A novel design of artificial aortic valve for transcatheter implantation.
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Delivery Device for Percutaneous Heart Valve

Delivery and recapture system and method for transcatheter prosthetic devices.
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Passive Wireless Detection System

A team of researchers at UCL's Department of Electronic and Electrical Engineering, have developed a method for detection and tracking using existing wireless signals (WiFi) present in the everyday environment.
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