LipoGlucoCEST – Novel Imaging Agents for GlucoCEST

2020-03-09T00:03:07+00:00

GlucoCEST is a magnetic resonance imaging (MRI) technique that enables visualisation of natural, non-radioactive glucose that can be used in cancer diagnosis. However, this technique has limitations due to interactions with the body glucose sensing system.

To solve this problem, researchers at UCL Institute of Neurology and Department of Chemistry have developed a novel set of imaging agents based on liposome-encapsulated sugar compounds that addresses these issues.

LipoGlucoCEST – Novel Imaging Agents for GlucoCEST2020-03-09T00:03:07+00:00

Collagen for tendon repair

2020-03-09T00:03:07+00:00

Collagen is the most widely distributed class of proteins in the human body and the use of collagen-based biomaterials in the field of tissue engineering is extensive. However collagen hydrogels typically have low mechanical strength, and accordingly may not be suitable for use in tendon and other tissue repair grafts without further processing. Whilst there are methods available to increase the strength of collagen, they are not suitable for fabrication of certain tissues as the shape of tissue needs to be “crafted” which leads to structural weakness, layer separation and heterogeneous cell distribution.

Collagen for tendon repair2020-03-09T00:03:07+00:00

Dengue Virus High-Throughput Fluorescent Assay

2020-03-09T00:03:06+00:00

We have developed a novel fluorescent assay for the screening of small molecules targeting dengue virus.

Dengue Virus High-Throughput Fluorescent Assay2020-03-09T00:03:06+00:00