World-first use of base-edited CAR T cells to treat resistant leukaemia

A 13-year-old girl with relapsed T cell leukaemia has been given base-edited T cells in a world-first use of a base-edited cell therapy, in a ‘bench-to-bedside’ collaboration between UCL and Great Ormond Street Hospital for Children (GOSH).

UCLB is supporting the team securing IP protection for the underlying technology.

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